| Compounds | Topics | Title | Date |
|---|---|---|---|
| CBD | anti-inflamatory,skin cancer in vitro | Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury | Jun 2019 |
| Down-regulation of genes involved in wound healing and skin inflammation was at least in part due to the presence of cannabidiol. Our findings provide new insights into the potential effect of Cannabisextracts against inflammation-based skin diseases. | |||
| WIN55,JWH-133 | cancer,skin cancer in mice via experiment | Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors | Jan 2003 |
|
Action Pathway: CB2 Local administration of the mixed CB1/CB2 agonist WIN-55,212-2 or the selective CB2 agonist JWH-133 induced a considerable growth inhibition of malignant tumors generated by inoculation of epidermal tumor cells into nude mice | |||
| cannabinoids | cancer,skin cancer via review | The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities | Jul 2009 |
| Collectively, it seems that the main physiological function of the cutaneous ECS is to constitutively control the proper and well-balanced proliferation, differentiation and survival, as well as immune competence and/or tolerance, of skin cells. | |||
| cannabinoids | cancer,skin cancer in mice | Cannabinoid receptors as novel targets for the treatment of melanoma. | Dec 2006 |
| Here, we evaluated the efficacy of cannabinoid receptor agonists, a new family of potential antitumoral compounds, at skin melanoma. Human melanomas and melanoma cell lines express CB1 and CB2 cannabinoid receptors. Activation of these receptors decreased growth, proliferation, angiogenesis and metastasis, and increased apoptosis, of melanomas in mice. | |||